RESISTANCE PHENOTYPES AND EPIDEMIOLOGICAL PROFILE OF BACTERIA ISOLATED FROM DIABETIC WOUNDS IN THE ENDOCRINOLOGY DEPARTMENT OF THE NATIONAL REFERENCE UNIVERSITY HOSPITAL OF N’DJAMENA, CHAD

Diabetic wound infection and antibiotic resistance remain a major concern for healthcare workers. The objective of this study was to contribute to improving the management of wounds in diabetic patients. This was a prospective, descriptive and analytical study, carried out from February 2022 to February 2023. The isolation and identification of bacteria were carried out according to standard clinical bacteriology techniques. Of the 104 diabetic patients with wounds, 80 cultures were positive, giving a prevalence of infection of 76.9%. The average age of the patients was 50 years with the extremes of 28 and 80 years. The sex ratio was 1.5. Type 2 diabetes predominated at 95%. The average duration of progression of diabetes was 8 years. The sampling site was feet in 77.5%. The predominant germs isolated were Staphylococcus aureus, (Escherichia coli), Staphylococcus spp, Proteus mirabilis with a rate of 32.1%, 28.7%, 21.8%, 8.05% respectively. This study made it possible to know the prevalence and frequency of bacteria involved in wound infections in diabetics. It also showed strong resistance of isolated bacterial strains to aminopenicillins and high sensitivities to imipenem and fusidic acid.