ACCURACY DETECTION SIGNIFICANT FIBROSIS OF LIVER OF SHEAR WAVE ELASTOGRAPHY IN 3 TYPES: 2D SWELOGIQ 9ETM, ELASTQ AND ELASTPQ

The proper evaluation staging of liver fibrosis is important for treatment such as begin antiviral treatment for patient significant fibrosis of liver (F >2) stop progression to cirrhosis and reverse to normal liver. Liver biopsy is gold standard but invasive method. There are many non-invasive methods as shear wave elastography. Transient elastography (Fibroscan) is the first and acceptance from many guidelines. There are new shear wave elastography technique pSWE and 2D-SWE that can be used in the same session of gray scale images. Objective: to evaluated the accuracy of 3 types of shear wave elastography (2D SWE LOGIQ 9ETM, ElastQ, ElastPQ for detection significant fibrosis (F > 2) using transient Elastography (TE) as the reference method. Method: 198 subjected with underlying liver disease, the LSMs by 3 SWE were evaluated in the same session for discriminated significant fibrosis and not significant fibrosis compare to the LSM by TE (fibroscan) for evaluation accuracy, sensitivity, specificity. Results: The LSM for the 3 SWE techniques can discriminate significant fibrosis (F> 2) from the non-significant fibrosis group even all give difference LSM value. All 3 types had good diagnostic performance AUROC curve (0.773-0.856) and high sensitivity (63.3-75.6%) and specificity (82.4-84.3%) accuracy (73.7-80.3%). The best cut-off LSM value for 2D SWE LOGIQ 9ETM, ElastQ, ElastPQ were 7 kPa, 5.7 kPa, 5.7 kPa respectively. Conclusion: SWE are good diagnostic performance and diagnostic test. The best cut-off LSM value for 2D SWE LOGIQ 9ETM, ElastQ, ElastPQ were 7 kPa,5.7 kPa, 5.7 kPa respectively