CANNABIS SATIVA: THE DIFFERENCE BETWEEN Δ8-THC AND Δ9-TETRAHYDROCANNABINOL (THC)

Cannabis (Cannabis sativa L.) is gaining popularity in the modern world through industrial, food, cosmetic, and medicinal uses. Although hemp can also be used for pharmaceutical purposes, it contains small amounts of Cannabinoids. Higher amounts of Cannabinoids can be produced in Cannabis varieties popularly known as “Medical Cannabis sativa (Marijuana or drug type). Phytocannabinoids are produced by the Cannabis sativa L. plant. They contain high levels of plant Cannabinoids, of which Cannabidiol (CBD) and Δ9-tetrahydrocannabinol are the most abundant and pharmaceutically most important. Δ8- tetrahydrocannabino (Δ8-THC) is an isomer or a chemical analog of Δ9-THC. Overall, the pharmacokinetics and pharmacodynamics of Δ8-THC and Δ9-THC are very similar. Δ8-THC is found naturally in Cannabis, though at substantially lower concentrations than Δ9-THC. Δ8-THC products may provide much of the experiential and therapeutic benefits of delta-9-THC with lower risks and lesser adverse effects. Further systematic research will be critical in verifying the favourable reports of Δ8-THC consumers.