CORRELATION BETWEEN 3 TYPE OF HEPATIC SHEAR WAVE ELASTOGRAPHY AND TRANSIENT ELASTOGRAPHY IN PREDICTION OF LIVER FIBROSIS

Background: Various type of non-invasive tests for the evaluation of liver fibrosis have been proposed, including transient elastography and shear wave elastography. Transient elastography (TE) is widely accepted modality but the correlation between TE and shear wave elastography (SWE) is still unclear. This study aims to evaluate the performance of 3 shear wave elastography methods in comparison with transient elastography within the same patient. Material and method: 198 patients with chronic liver disease who underwent multiple methods of elastography were retrospectively studied. The liver stiffness measurement (LSM) were obtained using 2D-SWE (LOGIQ9E), 2D-SWE ElastQ and P-SWE (ElastPQ) and compared to transient elastography (TE), which is used as the reference standard. Results and conclusion: The two 2D-SWE (LOGIQ9E and ElastQ) showed higher technical reliability rate of 98.3 % and 83.3%, respectively, in contrast with P-SWE (ElastPQ) (69.2%). 2D-SWE (LOGIQ9E) had better correlation with TE than 2D-SWE (ElastQ) and P-SWE (ElastPQ) with correlation value of 0.84, 0.61, and 0.61, respectively. The receiver operating characteristic (ROC) curve analysis for predicting significant fibrosis (> F2) yielded area under the ROC curve (AUROC) value base on TE of 0.77-0.87 indicating a strong correlation between these tests. The cut off value of 4.7 kPa for 2D-SWE (ElastQ), and 4.6 kPa for P-SWE (ElastPQ) could provide 81.1% sensitivity for the diagnosis of significant liver fibrosis (F≥ 2). Our study showed high reliability rate between all type of elastography. Among the 3 type, 2D-SWE (LOGIQ9E and ElastQ) provide a better reliability rate and correlation with TE than P-SWE.