DRUG LOADED ERYTHROCYTES:OPPORTUNITIES AND

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Author:

Shivali Tank, Kshitija Phatak, *Supriya Shidhaye

Country:

India

Volume & Issue:

Volume 03, Issue 05, May 2021

Page No:

1244-1251

Abstract:

Erythrocytes as an endogenous, biocompatible, multi-purpose carrier molecule have been explored for many years. Therapeutic molecules loaded erythrocyte delivery system has enhanced delivery of many synthetic and biological agents. Loading of these agents include internal loading as well as surface attachments. Various therapeutic agents have been used to deliver through Red Blood Cells which include anti-malarial drugs, anti-diabetic drugs, enzymes, proteins and peptides, antibodies etc. Advances in RBC-based delivery systems include RBC’s as nano carriers with the concept of nanoerythrosomes, design of stimuli responsive carriers etc. Hence, erythrocytes loaded drug delivery systems can be used as a multi-purpose cargo for delivery of various therapeutics agents, diagnostic agents etc. thereby enhancing clinical aspects of this delivery system.

KeyWords:

carrier, hitchhiking, nanoerythrosomes, stimuli sensitive, Theranostics.

IJISRR-518.pdf

Editorial Board Members

Dr.Anak Agung Gde Satia Utama

Assistant Professor

Airlangga University

Indonesia

Dr. Rudi Hartono, M.Pd

Associate Professor

Universitas Ibn Khaldun Bogor

Indonesia

Apsara Pandey

Assistant Professor

Tribhuwan University

Nepal

Bhupendra Chaudhary

Professor & HOD

India

Peymaneh Ghasemi Afshar

Assistant Professor

Islamic Azad University(I.A.U), Hidaj Branch, Zanjan,Iran

Iran

Michal Pankevič

Assistant Professor

Catholic University in Ružomberok, Slovakia

Slovak Republic

Md. Emam Hossain

Assistant Professor

Sher-e-Bangla Agricultural University

Dr. Mubarak

Associate Professor

Universitas Halu Oleo

Indonesia

Isabelita C. Bodbod

Professor

University of Science and Technology of southern Philippines

Philippines