Erythrocytes as an endogenous, biocompatible, multi-purpose carrier molecule have been explored for many years. Therapeutic molecules loaded erythrocyte delivery system has enhanced delivery of many synthetic and biological agents. Loading of these agents include internal loading as well as surface attachments. Various therapeutic agents have been used to deliver through Red Blood Cells which include anti-malarial drugs, anti-diabetic drugs, enzymes, proteins and peptides, antibodies etc. Advances in RBC-based delivery systems include RBC’s as nano carriers with the concept of nanoerythrosomes, design of stimuli responsive carriers etc. Hence, erythrocytes loaded drug delivery systems can be used as a multi-purpose cargo for delivery of various therapeutics agents, diagnostic agents etc. thereby enhancing clinical aspects of this delivery system.
DRUG LOADED ERYTHROCYTES:OPPORTUNITIES AND APPLICATIONS
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Country:
India
Volume & Issue:
Volume 03, Issue 05, May 2021
Page No:
1244-1251
Abstract:
KeyWords:
carrier, hitchhiking, nanoerythrosomes, stimuli sensitive, Theranostics.
