HISTOMORPHOLOGICAL ANALYSIS OF DIMINUTIVE AND SMALL POLYPS IN A TERTIARY CARE HOSPITAL

Background: Colorectal cancer is the major cause of morbidity and mortality. Colonoscopy examination is important for colorectal cancer screening effective in detection and removal of polyps and further histopathological examination plays a crucial role in patient management. The purpose of this study is to analyse the histomorphology of diminutive and small polyps detected during colonoscopy. Method: The cross sectional descriptive study was conducted at Hospital for Advanced Medicine and Surgery (HAMS). One hundred and thirty three patients underwent colonoscopy polypectomy followed by biopsy for confirmation of the lesion. Data were obtained and statistically analysed. Result: Out of 133 polyps, 89 (66.9%) of them were adenomas. 5 (22.7%) of the 81 diminutive polyps and 17 (77.3%) of the 52 small polyps showed advanced histology which was statistically significant (p value <0.0001). Conclusion: Polyp size plays an important role in determining the frequency of advanced adenomas as the small polyps has high frequency of showing advanced adenoma in comparison to diminutive polyps.