SEROPREVALENCE AND RISK FACTORS ASSOCIATED WITH TOXOPLASMA GONDII INFECTION AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE IN PLATEAU STATE SPECIALIST HOSPITAL, JOS, NIGERIA

Toxoplasmosis has been famously described as a cosmopolitan disease caused by the zoonotic parasite known as Toxoplasma gondii with the capacity to induce miscarriage and congenital defects during pregnancy. Despite its public health significance, there is a dearth of information about the epidemiology of the infection in pregnant women in Nigeria, consequently this study aimed to determine the burden and risk factors associated with T. gondii infection in pregnant women attending Ante-Natal Clinic (ANC) at Plateau State Specialist Hospital, Jos, Nigeria.3mls venous blood was collected from 268 pregnant women within the reproductive age groups of 15 to 50 years. Structured questionnaire was used to obtain demographic and Toxoplasma infection risk related data. Sera were assayed using a commercial ELISA kit (Novo Tec Immunodiagnostica® Germany). 46 out of the 268 women were positive with an overall prevalence rate of 17.16%. The highest prevalence was recorded among women within the age group ≤20 years (28.00%), urban settlers (18.18%), women in their second trimester 18.75%, those who owned cats (25.00%) and those who have contacts with cat’s faeces (29.10`%). There was a significant association (p < 0.05) between the prevalence of T.gondiiantibodies (IgG) with age, ethnic group and blood transfusion history. While other factors show no significant relationship (p>0.05). Asymptomatic Toxoplasmosisis common amongst pregnant women thus it is imperative for policy makers and caregivers to consider introducing routine screening of toxoplasmosis especially as part of antenatal program for pregnant women.