A REVIEW ON THE EFFECT OF TOXOPLASMOSIS ON HUMAN BEING

Toxoplasma gondii is an obligate intracellular protozoan parasite that infects all warm-blooded animals including humans. T.gondii infection cause development of central nervous system disorders, which may lead to altered behaviour in the affected individuals. The ingestion of raw and semi-cooked meat containing viable cysts has been suggested to be one of the major sources of infection. In the present investigation, the databases of PubMed, Google Scholar and Iran Doc were examined from 2000 to 2021 and related articles were reviewed. Review of related investigations revealed that T. gondii infection has been observed to play the greatest role in suicides, and psychiatric patients. It showed that T. gondii infection associate with schizophrenia, bipolar disorder, depressive disorder, addiction and obsessive-compulsive disorder. Besides, in severe cases the parasite may cross the placenta of an infected pregnant woman and probably infect the fetus congenitally. The current investigation is especially useful for health organization, pet owners, women and particularly pregnant women. Thus, consideration of the clinical factors, and laboratory results are important for diagnosis. Now more than ever, new strategies are desired to control T.gondii transmission.