ASSESSMENT OF IMMUNOLOGIC AND VIROLOGIC REQUEST TO ANTIRETROVIRAL TO PERSONS WITH AIDS FOLLOW-UP IN N’DJAMENA

This study at assessing the impact of antiretroviral treatment to the persons living with the Human immunodeficiency HIV, regularly follow-up at the General Hospital of National Reference in N’Djamena, and eligible to this treatment mainly to determine the progress of TCD4 lymphocyte rates and the viral load and to establish the correlation between observance and biologic evolution. The study was the longitudinal type on two years going from October 2011 to October 2013. The sample size was calculated by the Lorenz’s formula N= ² ² . In total 110 patients under antiretroviral replying to inclusion criteria were adopted for the study. The data gathered were controlled and printed thanks to software Epi Info version 7. The obtained results have showed that the CD4 median rates was of 173 cells/mm with an average of 188 of cases to JO, respectively against 599 CD4 620 to M24. Similarly to JO, the median of the viral load was at 24 070 copies/ul and 875.7 of average to 24th month. After twenty and four months of treatment, 94.54 % of our patients would recover their Immune competence, and 60% had undetectable viral load. This evolution is controlled at observance respectively( p= 0.009) for CD4 and ( P= 0.61). There forfeit high lights that the treatment efficiency was relatively good with a clinic improvement mainly a good kinetic of weight line.