BIOLOGICAL ACTIVITY OF SCHIFF BASES

Compounds containing an azomethine group obtained by condensation of a primary amine and an active carbonyl (CHO or RCOR) group are called "Schiff Base". Schiff bases constitute a special class of compounds used in organic chemistry, biochemistry, physical chemistry and coordination chemistry. In studies on Schiff bases and metal complexes, it has been determined that the synthesised compounds show many biological activities such as antibacterial, analgesic, antifungal, anticancer, anti-inflammatory, anti-HIV, antimalarial. These properties have increased the interest in Schiff bases and metal complexes and encouraged intensive studies on their biological activities. Schiff base and its derivatives are widely used in medicine and pharmacy. In line with these findings, it has been determined that Schiff base and its complexes show promising activity on biological systems. It is thought that they can be used as a lead and active compound for future drug design studies and will contribute to the literature knowledge.