KINETIC AND MECHANISTIC STUDY OF OXIDATION OF NIACIN (VITAMIN-B3) BY SODIUM NCHLORO TOLUENESULPHONAMIDE (CHLORAMINE-T) IN HCL MEDIUM

Kinetic and mechanistic investigation of oxidation of Niacin [Vitamin-B3 ] using chloramine-T as an oxidant in hydrochloric acid medium has been studied at 303K. Reaction shows a first order dependence of the rate on oxidant [CAT] and Niacin concentration, and inverse fractional order in concentration of hydrochloric acid. Addition of reduction product of chloramine-T toluenesulphonamide , chloride ion, variation of ionic strength and dielectric constant of the medium do not have any significant effect on the rate of the reaction. The activation parameters of the reaction have been computed from the Arrhenius plot. A derived rate law and mechanisms are consistent with obtained experimental results.