UNCERTAINTIES ON RECENT VACCINES’ FEASIBILITY AGAINST SARS-COV-2; POSTULATING NEW APPROACHES ON DRUG-VACCINE DEVELOPMENT; AND SCHEMATIZING THE POSSIBLE OPTIONS FOR INVESTIGATING THE ORIGIN OF A PATHOGEN

Infectious diseases are still one of the mass killers. Among them the COVID-19, which caused by a virus SARS-CoV-2 (whose nature is yet not well investigated), is an old-new respiratory infectious disease. This pandemic already took around 1.5 million lives, destructing the socioeconomic structure of the globe. To combat it world is trying the possible-impossible measures. For instance, at the beginning of the pandemic, around hundred research sites were announced about their engagement in drug-vaccine discovery activities. Today, using the Media as a battle of field, developed countries change the vaccine discovery issue into business and political oriented race. Certainly, vaccines, as one of prevention based prophylaxis measures are used earlier too. However, we are afraid that world doesn’t distinguish – against which pathogen can achieve feasible vaccine!! Yes, when Media announced as if tomorrow will be developed vaccine to contain COVID-19 pandemic, since March 29, 2020, we are twitting and publishing that for such type of virus and moreover within short of time frame, it is impossible to have practicable vaccine. Rather, we are saying: the cheapest, fastest but effective ways of preventive measures (not to be infected and not to infect others) are: scaling up the public’s awareness on the nature of SARS-CoV-2; guiding nations on how to use properly the sanitationhygiene based prophylaxis measures; seriously take into account the two decisive prevention measures: “stay at home (but not lock down)” and “safe (but not face) masking”; and we tried to caution that a vaccine discovery hope can idle the public and make him negligent for the pandemic. Therefore, after awaiting the results of vaccine discovery duel for 9 months, we decided to publish our biochemistry-physiology-anatomy and literature review based research work to point out our suspicion-doubts on nature and recent vaccines against the pathogen. In this work: in a scheme form, we list more than 13 possible paths on how to identify SARS-CoV-2’s and others future pathogens’ initial sources; we have elaborate 5+1 groups of scientific justifications, why recent vaccines may not be feasible against corona virus; and as a potential solution, we hypothesized how better to direct the drug-vaccine discovery’s activities for such type of pathogens.