POSSIBLE QUINCUNCIAL AND SCISSORING INTERVENTION OF ANAGEN GROW IN 5α- REDUCTASE CASCADE AND HAIR GROWTH PROMOTING EFFECT

Alopecia or baldness is although a part of aging process where many bio-chemical aspects in mammalian system undergoes irreversible change, hair root cell activation and inactivation of alpha reductase enzyme may partly decrease the problem of hair loss. Anagen grow, in the present study proves that the phytoconsitiunets in the formulation increases hair follicle cell activation and alpha reductase enzyme inhibition which in-turn hinder DHT conversion the culprit of hair follicle atrophy. We have employed Rat liver microsomal preparation was used as enzyme source wherein finasteride as positive control. The EGCG like constituent in the formulation is implicated for the above activity, details are presented in the paper.