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RISQUE CARDIOVASCULAIRE AU COURS DE LA POLYARTHRITE RHUMATOIDE (PR) : A PROPOS DE 20 CAS A BOUAKE

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Author: 
*Traore Aissata Doucoure, Koffi Enock Joseph, Wognin Manzan Edwige Anastasie, Yao Konan Joe-Clauvis, Goua Jean Jacque, Kouakou Ehaulier Soh Christian, We Tia Melanie, Daboiko Felix Jean-Claude
Country: 
Côte d’Ivoire
Volume & Issue: 
Volume 06, Issue 09, September 2024
Page No: 
6943-6946
Abstract: 

Objectif : Notre objectif était de déterminer la fréquence des facteurs de risques cardiovasculaires (FRCV) au cours de la PR à Bouaké. Patients et méthodes : Étude rétrospective à visée descriptive menée au service de rhumatologie du centre hospitalo-universitaire (CHU) de Bouaké sur une période de 3 ans (2018-2022) colligeant 20 patients ayant une PR. Ont été inclus les dossiers de patients souffrant d’une polyarthrite rhumatoïde répondant aux critères de l’ACR 1987 et de l’ACR-EULAR 2010 avec au moins un facteur de risque cardiovasculaire (FRCV). Nous avons étudié la présence des FRCV suivant : tabagisme, hypertension artérielle (HTA), diabète, dyslipidémie, hyperuricémie, hypercréatininemie et obésité. Résultats: Le sexe- ratio H/F était 0,17 (3H et 17 F). L’âge moyen de nos patients était de 44,85 ans [18–64]. La durée moyenne d’évolution était de 42,80 mois [1–120]. Quinze patients étaient sous corticothérapie avec une dose moyenne de 10 mg/jour. L’ensemble de nos patients était sous méthotrexate (MTX) à la dose moyenne de 9,5 mg/semaine. Les FRCV déterminés au cours de la PRserépartissaient comme suit : dyslipidémie (35%), HTA (30%), obésité (25%), tabagisme (20%), surpoids (15%), hypercréatininemie (10%), diabète (5%), hyperuricémie (5%)et un cas de cachexie rhumatoïde. Six patients (30%) avaient au moins deux FRCV. Les patients ayant au moins un FRCV avaient une maladie plus active (DAS 28 VS moyen = 4,96). La présence de facteur rhumatoïde et/ou anti-CCP était mise en évidence chez (50%) 10 patients. Conclusion: Les FRCV sont fréquents au cours de la PR à Bouaké. Ils sont dominés par la dyslipidémie, l’HTA et l’obésité. En plus des FRCV classiques, la PR est elle-même est décrite comme un FRCV indépendant. Il est donc important pour tout praticien d’évaluer ces FRCV dans le suivi des patients souffrant de PR selon les recommandations. Un meilleur contrôle de l’activité est nécessaire pour un plus faible risque CV.

KeyWords: 
Adolescence, Menstruation, Menstrual hygiene.