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INTRAVENOUS ANTIBIOTIC SALVAGE THERAPY IN SEVERE FALCIPARUM MALARIA: ROLE OF TIGECYCLINE?

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Author: 
Arash Eatemadi, Mohammed Abbas Bokhari, Elham Mohammed Abdalla, Khalafellah Ali Osman, Heytham Adam Mustafa, Musaab Mohmed Zaroug, Islam TajelsirrAwad
Country: 
Oman
Volume & Issue: 
Volume 03, Issue 02, February 2021
Page No: 
847-848
Abstract: 

Malaria chemotherapy remain a major area of research, and new drug molecules are constantly being developed before drug-resistant plasmodium strains emerge. Some antibiotics that have shown potential effects on malaria parasite have been recently studied in vitro or in vivo intensively. Antibiotics with antimalarial activity, in combination with traditional anti-malarial drugs, are potentially useful options for drug-resistant, uncomplicated as well as complicated cases of malaria. As an exclusively parent rally administered antibiotic, tigecycline may represent an alternative drug for treating patients with severe and complicated Plasmodium falciparum malaria.

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